It also became Mars' fastest song to reach number one.

It became Paak's first number one song on the Hot 100. It was the most-sold song of the week, with two CD versions that shipped to purchasers in that week. On the week of April 12, 2021, the song topped the Billboard Hot 100 with 28,600 copies (downloads and CDs sales combined), 21.5 million streams and 59.1 million radio impressions. On the following week, the single reached number two on the Billboard Hot 100, behind Cardi B's 'Up' (2021).

At the time, it was Mars and Paak's highest debut on the Billboard Hot 100. 'Leave the Door Open' debuted at number four on the US Billboard Hot 100 with 27,000 downloads, 23.5 million streams and 23.5 million radio impressions on the week of March 15, 2021. On March 5, 2021, shortly after the announcement of An Evening with Silk Sonic, 'Leave the Door Open' was released as the first single of the aforementioned project alongside the 'Silk Sonic Intro'. In late February 2021, Bruno Mars and Paak announced on social media platforms the formation of their new band Silk Sonic and group's first studio album An Evening with Silk Sonic.

It goes to like, 'I can't wait till people hear this.' And it's also, 'I can't wait to play this for people. He added, 'A lot of meat went into this song.' Mars lamented the lack of live performances due to the COVID-19 pandemic, adding 'While I'm writing songs, that's a part of my whole thing.

Paak said the song required a lot of 'patience and delicate' to create. In an interview with New Zealand radio DJ Zane Lowe for the Apple Music podcast Beats 1, Anderson.

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